Well, it seems another possible
answer has been found.
Perhaps more so a variation of a few former theories.
Let's look it this by examining
a few links, and a
brief few descriptions. That way we can simply use
the words of the experts. Since it has become difficult
and time consuming to constantly research and link
the newest theory every three to six months.
As of January 12th, 2000. This is the "latest" theory.
* Missing Protein Linked to Narcolepsy
Reuters - December 31, 1999
NEW YORK, Dec 31 (Reuters
Health) -- A protein normally found in spinal fluid appears to be lacking
in many patients with the sleep disorder narcolepsy,
according to a new
The findings suggest that the protein, called hypocretin 1, could play a role in treating the ailment, which causes sudden sleep attacks that can occur many times a day.
"We now know that hypocretin 1 is involved in narcolepsy in humans, and if we supplement hypocretin 1 we may be able to dramatically improve the symptoms of the disorder," Dr. Seiji Nishino said in an interview with Reuters Health.
"We also know where to look in the human brain and how to study hypocretin 1," he said. "If we find (hypocretin 1's) mechanism, we may be able to prevent (narcolepsy) and cure the disease."
Nishino and colleagues from Stanford University compared the amount of hypocretin 1 found in the spinal fluid of nine individuals with narcolepsy and eight healthy individuals. In a research letter in the January 1st issue of The Lancet, they report that hypocretin 1 was "undetectable" in seven of the nine narcolepsy patients but was seen in all of the other individuals.
believes that the findings can be used to help diagnose narcolepsy.
It is estimated that 1.6 people per thousand in Europe, Japan and the United
States are affected by the disorder, which is usually treated
with stimulants and
antidepressants. SOURCE: The
Stanford University Sleep Clinic
and postsynaptic actions and modulation of
neuroendocrine neurons by a new hypothalamic peptide,
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